Serpiginous-like choroiditis as sign of intraocular tuberculosis
نویسندگان
چکیده
BACKGROUND Tuberculosis is a world-wide public health problem which may clinically present in many different ways. Here we report on a patient with presumed serpiginous choroiditis (PSC) found to have latent ocular tuberculosis. CASE REPORT The clinical history and physical examination, complete blood count, erythrocyte sedimentation rate, chest radiograph, fundus fluorescein angiography, tuberculin skin test, serological tests, and systemic evaluation carried out by consultant internist of a 42-year-old man with PSC were evaluated. The patient presented with gradual painless loss of central vision in his left eye and dark rings in the central visual field of the right eye. Upon examination, he was found to have 1 round choroidal lesion centered in the left macula and multiple serpiginous-like choroidal lesions in the right eye. Based on positive tuberculin skin test result, the patient was initially treated with anti-tubercular therapy combined with systemic corticosteroids. An immunosuppressive agent (Azathioprine) was consequently administered due to unsatisfactory response to initial therapy and the vicinity of the pathological process to the right fovea. CONCLUSIONS It is important to remember that tubercular choroiditis may present with clinical features of serpiginous choroiditis, requiring timely and appropriate therapy and close observation in order to prevent the progression of visual loss and recurrences.
منابع مشابه
Tuberculous uveitis: distribution of Mycobacterium tuberculosis in the retinal pigment epithelium.
The diagnosis of intraocular tuberculosis has been a challenge until the introduction of polymerase chain reaction (PCR) to detect the mycobacterial-specific DNA sequence in the intraocular fluids. Such investigations have confirmed diverse manifestations of intraocular tuberculosis including retinal vasculitis and serpiginouslike choroiditis. The latter may manifest with multifocal lesions inv...
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CASE REPORT We report the case of a 70-year-old patient with serpiginous choroiditis and uterine cervix carcinoma. DISCUSSION The etiology of serpiginous choroiditis is unknown, but similar lesions have been described in association with systemic lupus erythematosus, non-Hodgkin lymphoma, Crohn's disease, sarcoidosis, tuberculosis, herpes virus infection, autoimmune hepatitis and lung carcinoma.
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Purpose To report a novel clinical sign in patients with intraocular tuberculosis. The current study is an observational consecutive case series of patients diagnosed with intraocular tuberculosis managed at a tertiary eye care centre from June 1, 2012 to December 31, 2015. Observations The diagnosis of intraocular tuberculosis was made in 6 patients based on ocular features suggestive of tub...
متن کاملParadoxical Worsening of Tubercular Serpiginous-Like Choroiditis after Initiation of Antitubercular Therapy
In this study, a case with tubercular choroiditis showing severe macular edema and progression of choroidal lesions following initiation of antitubercular treatment is presented and the management of posterior uveitis associated with tuberculosis is evaluated. A 40-year-old female patient was admitted with decreased vision in her right eye and her fundoscopic examination revealed serpiginous ch...
متن کاملClinical features of tuberculous serpiginouslike choroiditis in contrast to classic serpiginous choroiditis.
OBJECTIVE To compare distinctive clinical features of presumed tuberculous serpiginouslike choroiditis (Tb-SLC) with classic serpiginous choroiditis (SC) in patients living in a region that is nonendemic for tuberculosis. METHODS Retrospective comparative analysis of clinical features of 5 patients with recurrent Tb-SLC and 5 with SC. RESULTS All patients with recurrent Tb-SLC primarily emi...
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عنوان ژورنال:
دوره 17 شماره
صفحات -
تاریخ انتشار 2011